AB-FUBINACA 2-fluorobenzyl isomer
Buy AB-FUBINACA 2-fluorobenzyl isomer is a designer drug identified in synthetic cannabis blends in Japan in 2013. In 2018, it was the third-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Agency.
The (S)-enantiomer of AB-FUBINACA 2-fluorobenzyl isomer is described in a 2009 Pfizer patent and has been reported to be a potent agonist of the CB1 receptor and the CB2 receptor with EC50 values of 1.2 nM and 3.5 nM, respectively. AMB-Fubinaca Powder features a carboxamide group at the 3-indazole position, like SDB-001 and STS-135. MDMB-FUBINACA Powder appears to be the product of rational drug design, since it differs from AMB-Fubinaca only by the replacement of the isopropyl group with a tert-butyl group.
An analogue of MDMB-FUBINACA Powder, ADSB-FUB-187, containing a more functionalized carboxamide substituent was recently reported.
Technical Information
Formal Name: N-[1-(aminocarbonyl)-2,2-dimethylpropyl]-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide
CAS Number: 1445583-51-6
Molecular Formula: C21H23FN4O2
Formula Weight: 382.4
Purity: ?98%
Formulation: A neat solid
SMILES: O=C(NC(C(N)=O)C(C)(C)C)C1=NN(CC2=CC=C(F)C=C2)C3=C1C=CC=C3
InChi CodeInChI=1S/C21H23FN4O2/c1-21(2,3)18(19(23)27)24-20(28)17-15-6-4-5-7-16(15)26(25-17)12-13-8-10-14(22)11-9-13/h4-11,18H,12H2,1-3H3,(H2,23,27)(H,24,28)
InChi Key: ZSSGCSINPVBLQD-UHFFFAOYSA-N
DEA Schedule: I
Shipping & Storage Information
Storage: -20°C
Shipping: Room Temperature in continental US; may
vary elsewhere
Stability: ? 3 years
Legality
In the United States, AMB-Fubinaca is
a Schedule I controlled substance.
Metabolism
Twenty-three AMB-Fubinaca major metabolites were identified in several incubations with cryopreserved human hepatocytes. Major metabolic pathways were alkyl and indazole hydroxylation, terminal amide hydrolysis, subsequent glucuronide conjugations, and dehydrogenation
Side effects
One death through coronary arterial thrombosis has been linked to
AB-FUBINACA 2-fluorobenzyl isomer intoxication.
At least an additional 8
deaths in Hungary in 2015 are linked to the usage of this material, all deaths were youngsters below 21.
WARNING This product is not for human or
veterinary use.
